Aspergillus

Defend Against Invasive Aspergillosis

Invasive Aspergillosis (IA) is a life-threatening fungal infection caused by Aspergillus, predominately affecting immunocompromised individuals. Most people breathe in Aspergillus spores every day without getting sick. However, immunosupressed people are at a higher risk of developing health problems due to Aspergillus. Nosocomial outbreaks of aspergillosis have become a well recognized complication of construction, demolition or renovation activities in or near hospital wards. Aspergillus spores are superbly adapted to airborne dissemination. Invasive aspergillosis (IA) is a leading cause of mortality in patients with acute leukemia.

IA in Leukemia Patients

A study published in Clinical Infectious Diseases observed the implications associated with IA in leukemia patients. The study found that:

  • 80 of the 269 patients developed IA
  • Total IA-related costs increased to €8,360 – €15,280 ($9,000 – $17,000) for IA patients, compared with patients without IA
  • The overall mortality rate was 26% in patients with IA versus 16% in patients without IA.

Source: Clinical Infectious Diseases

IA and Mortality

IA continues to have substantial attributable mortality combined with a major impact on hospital resource use, so effective prevention in high-incidence populations has the potential to save lives and costs.

Source: Clinical Infectious Diseases